First, understand the simplest form of the expression:
When you are teaching Origami, you would say:
Fold it like this.
So, the expression by itself does not speak to health, appearance, folding, or flavor. Quite simply, "like this". So it depends on what follows.
In summer, you can dress it up LIKE THIS.
Now, let's make the statement above a question.
How do you dress in Summer?
Notice how it became simply "How".
Now, let's get back to your original.
This is a conjugation of する(do) in progressive tense.
So, in the end it's quite literally:
How was Yamada doing?
Since it does not specify what it is about, it could be anything.