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I want to ask a person about their hobbies. Go/O shumi ha nan desu ka? 趣味
It's ご趣味. As a general rule for nouns, ご beautifies a word which uses the on-yomi (e.g. ご質問 or ご主人), while お beautifies a word which uses the kun-yomi (e.g. お米 or お金).
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