1

This form is usually translated as "regardless"; however its meaning seems to be pretty similar to をよそに and to をものともせず. Is their usage different?

2

Grammatically, ~をよそに, ~をものともせず and ~にも構わず work similarly. However there is a difference in meaning.

  • 構う can mean "to worry about", "to look after", etc. Thus ~に構わず tends to be used for something/someone people should normally care about, such as a dying ally and an advice of your friend. も adds the nuance of "even".
  • When you use ~をものともせず, the target is normally a direct obstacle or hardship you should endure, such as a storm, an enemy attack and a torture. It's used to describe the strength or boldness of the subject.
  • 余所【よそ】 means "other (irrelevant) places". ~をよそに means the speaker is not interested in something at all in the first place.
  • Thank you so much, it was really helpful! Sorry if I'm awfully late, but I don't know why, but I missed the notification! – Alex16 Jan 19 '18 at 8:48

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