3

ここには 1人(  ) しっている 人が いません。

(from #25 of http://jlpt.u-biq.org/3g1.html)

A) が      B) は      C) で      D) も

I know the answer is D, but what does the sentence mean? If しっている with kanji is 知っている, then I can guess the idea is "There isn't one person here I know"?

5

Yes, the sentence means exactly as you guessed.

「Indefinite word + も」 expresses either total affirmation or total negation.

「ひとりいません」= "there is no one"

「ひとり知{し}っている人がいません」= "there is no one that I know"

The sentence in question would make no sense whatsoever if any of the other three particles were inserted.

Other examples of this usage of 「も」:

Total affirmation: 

「だれが知っているレストラン」("the restaurant that everyone knows of")

「ゴールデンウイークはどこ混{こ}んでいる。」("Every place is packed during the Golden Week.")

Total negation:

「なに知りません」("I know nothing.")

「もうだれ愛{あい}せない。」(I could not love anyone any more.)

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